ASUS Prime TRX40-Pro S
Built for Heavy-Duty Workstations
The ASUS Prime TRX40-Pro S is an ATX motherboard designed for AMD's 3rd Gen Ryzen Threadripper processors (sTRX4 socket). It targets content creators, engineers, and data scientists who need massive multi-core performance and extensive I/O. With eight DDR4 slots supporting up to 256GB in quad-channel mode, it handles memory-intensive tasks like 3D rendering, video editing, and virtual machines with ease.
Key Features
- Powerful VRM: A robust power delivery system with two 8-pin EPS connectors ensures stable operation even under sustained full-core loads. A dedicated fan mount for the VRM heatsink is included for extra cooling.
- PCIe 4.0 Expansion: Three PCIe 4.0 x16 slots (x16, x16/x16, x16/x16/x16) and one PCIe 4.0 x4 slot provide ample bandwidth for multiple GPUs and high-speed add-in cards. Support for 2-way SLI and CrossFire is present.
- Storage Flexibility: Three M.2 slots (one PCIe 4.0 x4/SATA, two PCIe 4.0 x4) plus eight SATA 6Gb/s ports offer extensive storage options. A vertical M.2 mount is included for the third drive.
- Connectivity: Intel I211-AT Gigabit LAN, Realtek S1220 8-channel audio, USB 3.2 Gen 2 Type-C front header, and a pre-mounted I/O shield with BIOS FlashBack for easy updates.
- DIY Friendly: Aura Sync RGB headers, Q-Connector, and a comprehensive accessory package simplify building and customization.
Performance Highlights
In professional reviews, the board demonstrated excellent memory bandwidth, achieving over 87,000 MB/s read and 88,000 MB/s write in AIDA64 with DDR4-3200. Rendering benchmarks like Corona and Fryrender completed quickly, showcasing the platform's strength for multi-threaded workloads. The 8-phase (likely 16+4) power stage delivered stable voltages during overclocking tests.
Who Is It For?
This motherboard is ideal for professionals building a high-end AMD workstation for video production, CAD, scientific computing, or machine learning. It offers a balance of performance, expansion, and reliability without the premium price tag of flagship TRX40 boards. If you need a dependable foundation for a Threadripper-based system, the Prime TRX40-Pro S is a compelling choice.
Key Specifications
Detailed Parameters
- Platform:
- AMD
- Socket:
- TRX4
- RAM Type:
- DDR4
- Number of RAM Slots:
- 8
- Maximum RAM/slot:
- 32
- Maximum RAM Capacity in GB:
- 256
- PCI Express Version:
- 4
- Form Factor:
- ATX
- Maximum RAM Speed in MHz:
- 4666
- ECC:
- Yes
- Chipset:
- TRX40
- SupportedPlatforms:
- AMD Workstation
Pros
- Robust power delivery with dual 8-pin EPS and optional VRM fan mount
- Three PCIe 4.0 x16 slots support multi-GPU configurations
- Eight DDR4 slots with quad-channel support up to 256GB
- Triple M.2 slots (including PCIe 4.0) and eight SATA ports for extensive storage
- Comprehensive USB connectivity including front-panel USB-C
- Pre-mounted I/O shield and BIOS FlashBack simplify installation
Cons
- Only Gigabit LAN, no 2.5G or Wi-Fi included
- No integrated RGB lighting, though headers are provided
- M.2 Key E slot requires careful Wi-Fi card selection (CNVi vs PCIe)

