ASUS Prime TRX40-Pro S

ASUS Prime TRX40-Pro S

Motherboard • ASUS • $ 649.99

Share This Component

Built for Heavy-Duty Workstations

The ASUS Prime TRX40-Pro S is an ATX motherboard designed for AMD's 3rd Gen Ryzen Threadripper processors (sTRX4 socket). It targets content creators, engineers, and data scientists who need massive multi-core performance and extensive I/O. With eight DDR4 slots supporting up to 256GB in quad-channel mode, it handles memory-intensive tasks like 3D rendering, video editing, and virtual machines with ease.

Key Features

  • Powerful VRM: A robust power delivery system with two 8-pin EPS connectors ensures stable operation even under sustained full-core loads. A dedicated fan mount for the VRM heatsink is included for extra cooling.
  • PCIe 4.0 Expansion: Three PCIe 4.0 x16 slots (x16, x16/x16, x16/x16/x16) and one PCIe 4.0 x4 slot provide ample bandwidth for multiple GPUs and high-speed add-in cards. Support for 2-way SLI and CrossFire is present.
  • Storage Flexibility: Three M.2 slots (one PCIe 4.0 x4/SATA, two PCIe 4.0 x4) plus eight SATA 6Gb/s ports offer extensive storage options. A vertical M.2 mount is included for the third drive.
  • Connectivity: Intel I211-AT Gigabit LAN, Realtek S1220 8-channel audio, USB 3.2 Gen 2 Type-C front header, and a pre-mounted I/O shield with BIOS FlashBack for easy updates.
  • DIY Friendly: Aura Sync RGB headers, Q-Connector, and a comprehensive accessory package simplify building and customization.

Performance Highlights

In professional reviews, the board demonstrated excellent memory bandwidth, achieving over 87,000 MB/s read and 88,000 MB/s write in AIDA64 with DDR4-3200. Rendering benchmarks like Corona and Fryrender completed quickly, showcasing the platform's strength for multi-threaded workloads. The 8-phase (likely 16+4) power stage delivered stable voltages during overclocking tests.

Who Is It For?

This motherboard is ideal for professionals building a high-end AMD workstation for video production, CAD, scientific computing, or machine learning. It offers a balance of performance, expansion, and reliability without the premium price tag of flagship TRX40 boards. If you need a dependable foundation for a Threadripper-based system, the Prime TRX40-Pro S is a compelling choice.

Key Specifications

Form Factor: ATX (305 × 244 mm)
Socket: TRX4
RAM Type: DDR4 (XMP up to 4600+), quad-channel, 8 slots
Max. RAM: 256GB
RAM Slots: 8
Chipset: AMD TRX40
Connectivity
3X PCIe 4.0 x16 (x16, x16/x16, x16/x16/x16), 1X PCIe 4.0 x4, 1X M.2 Key M 2242-2280 (PCIe 4.0 x4 / SATA), 2X M.2 Key M 2242-22110 (PCIe 4.0 x4), 1X M.2 Key E 2230 (PCIe 3.0 x2, for Wi-Fi), 8X SATA 6 Gb/s, 1X Intel I211-AT 1 GbE LAN, Realtek S1220 8-channel audio, Aura Sync RGB headers, pre-mounted I/O shield, BIOS FlashBack
Back Panel IO
6X USB 3.2 Gen 1 Type-A, 3X USB 3.2 Gen 2 Type-A, 1X USB 3.2 Gen 2 Type-C, 1X Intel 1 GbE LAN, 5X audio jacks, 1X optical S/PDIF out, 1X BIOS FlashBack button
Onboard USB Headers: 1X USB 3.2 Gen 2 front-panel Type-C header 2X USB 3.2 Gen 1 headers (4 ports) 2X USB 2.0 headers (4 ports)

Detailed Parameters

Platform:
AMD
Socket:
TRX4
RAM Type:
DDR4
Number of RAM Slots:
8
Maximum RAM/slot:
32
Maximum RAM Capacity in GB:
256
PCI Express Version:
4
Form Factor:
ATX
Maximum RAM Speed in MHz:
4666
ECC:
Yes
Chipset:
TRX40
SupportedPlatforms:
AMD Workstation

Where to Buy

Pros

  • Robust power delivery with dual 8-pin EPS and optional VRM fan mount
  • Three PCIe 4.0 x16 slots support multi-GPU configurations
  • Eight DDR4 slots with quad-channel support up to 256GB
  • Triple M.2 slots (including PCIe 4.0) and eight SATA ports for extensive storage
  • Comprehensive USB connectivity including front-panel USB-C
  • Pre-mounted I/O shield and BIOS FlashBack simplify installation

Cons

  • Only Gigabit LAN, no 2.5G or Wi-Fi included
  • No integrated RGB lighting, though headers are provided
  • M.2 Key E slot requires careful Wi-Fi card selection (CNVi vs PCIe)

Frequently Asked Questions

Does the ASUS Prime TRX40-Pro S support ECC memory?

Yes, the motherboard supports ECC memory when used with compatible AMD Ryzen Threadripper processors. However, ECC functionality may depend on the specific memory modules and CPU model.

What is the maximum memory capacity and speed?

The board has eight DDR4 slots and supports up to 256GB total capacity. With XMP profiles, memory speeds up to 4666 MHz (OC) are achievable, though official support is up to 3200 MHz for the platform.

Can I use multiple GPUs with this motherboard?

Yes, the three PCIe 4.0 x16 slots support 2-way NVIDIA SLI and AMD CrossFire, and even 3-way CrossFire for compatible cards. The slots operate in x16, x16/x16, or x16/x16/x16 modes depending on configuration.

Does it have built-in Wi-Fi?

No, Wi-Fi is not included. However, there is an M.2 Key E slot (PCIe 3.0 x2) for installing a Wi-Fi card. ASUS recommends using Intel AX200; avoid CNVi-based cards like the 9260 or AX201.

What processors are compatible with the TRX4 socket?

The TRX4 socket supports AMD Ryzen Threadripper 3rd Gen processors (e.g., 3960X, 3970X, 3990X). It is not compatible with older TR4 or newer sTRX4 CPUs.

Compare ASUS Prime TRX40-Pro S with Similar Motherboards

ASUS Prime TRX40-Pro S
VS

You cannot copy content from this page

Scroll to Top